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Promising Targets Discovered for Rare Brain Disorder PSP

Summary: Researchers have identified new therapeutic targets for progressive supranuclear palsy (PSP), an incurable brain disorder with symptoms mimicking Parkinson’s and dementia. The study focused on RNA sequencing from brain samples of over 400 individuals. By analyzing almost 5,000 genes linked with PSP, the team prioritized 11 high-confidence genes. Reducing levels of DDR2, KANK2, and …


Psilocybin Microdosing Promising for Mental Health Disorders

Summary: Researchers delve into the therapeutic potential of psilocybin microdosing, exploring its influence on stress resilience and compulsive behaviors in rats. While high-dose psilocybin therapy has been scrutinized for psychiatric treatment applications, this study focuses on low, repeated doses—commonly known as ‘microdosing’—and its burgeoning popularity in self-medication narratives online. Findings reveal not only a tolerance …