Summary: Researchers have revealed a groundbreaking role of RNA in fear-related learning and memory. Their study shows how noncoding RNA Gas5 influences neuronal excitability, impacting learning and memory processes. Another study identified m6A-modified RNAs that regulate synaptic plasticity, crucial for fear extinction memory, a key factor in PTSD. These findings offer new insights into RNA’s …
PTSD
Brain Activity in PTSD: Trauma Memories Differ from Sad Ones
Summary: A new study reveals distinct differences in brain activity between traumatic memories in PTSD patients and regular sad autobiographical memories. This research, the first of its kind to examine real-life personal memories, found that traumatic memories do not activate typical memory-related brain regions like the hippocampus, suggesting they’re not processed as regular memories. Instead, …
Ketamine’s Surprisingly Swift Treatment of PTSD and Depression
By C. Michael White, University of Connecticut November 18, 2023 The drug ketamine shows promise in rapidly reducing PTSD and depression symptoms, according to a recent study published in the Annals of Pharmacotherapy. While traditionally used as an anesthetic and sometimes misused, ketamine’s potential in mental health treatment is being explored. Recent research indicates that …
Cortisol’s Role in PTSD Vulnerability
Summary: Researchers discovered how stress-induced hormones like cortisol influence the likelihood of developing PTSD. Using a rat model with a blunted hormonal response to stress, they observed impaired fear extinction, reduced hippocampal volume, and sleep disturbances, all traits associated with PTSD. Treatment combining cognitive therapy with corticosterone helped alleviate these symptoms, offering insights into potential …
Microbiome and Diet Could Mitigate PTSD Symptoms
Summary: Researchers explored the potential link between the Mediterranean diet, the gut microbiome, and PTSD symptoms. Their study, involving 191 participants, revealed that those following a Mediterranean diet exhibited fewer PTSD symptoms. A notable discovery was the presence of Eubacterium eligens, a bacteria positively associated with key components of the Mediterranean diet, which showed consistent …
Greater Manchester hospital trust apologises after failings in care left teen with PTSD
A Greater Manchester hospital trust has apologised after medics missed symptoms of sepsis in a teenager, leaving her with PTSD. Ella Watts attended the A&E department at The Royal Albert Edward Infirmary in Wigan with flu-like symptoms, chest pain, vomiting and diarrhoea in December 2018. She was triaged as a category three patient, and decided …
Skelmersdale teen left with PTSD after hospital missed sepsis infection
A young woman says she was left with PTSD after medics missed the signs of a sepsis infection – delaying her treatment by 24 hours. On 8 December 2018, Ella Watts, from Skelmersdale, attended the A&E department at The Royal Albert Edward Infirmary in Wigan with her mum Julia Watts. She had flu-like symptoms, chest …